Enterobius vermicularis drug of choice


Sunteți pe pagina 1din 1 Căutați în document Treatment Albendazole is the drug of choice, administered for a total of 3 days.

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Repeat pharmacologic therapy may be required because the treatment is not very ef? Oral mebendazole is an alternative.

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Enterobius vermicularis Pinworm Epidemiology The pinworm is the most common he lminth of industrialized nations and temperate climates. The pediatric populatio n in particular is prone to infection, as are situations of crowding. Mature eggs are ingested by the host, usually by hand contamination.

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The eggs hatch in the duodenum, and the larvae develop to maturity in the small intestine, proceed to the large intestine, and reside there, growing up to 13 mm long females.

Gravid females migrate out of the anus and lay their eggs on th e perineum, from where pruritus may reinfect the host by means of oral transmiss ion. The eggs can survive for weeks outside the human host, and can remain in un washed clothing.

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Alternative routes of reinfection of the host are by the hatche d worms re-entering the rectum from the anus and perineum, and back into the col on; the eggs removing papilloma from eyelid fully infective within a few hours of being deposited Fig.

Clinical Presentation Most infections are believed to be asymptomatic.

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Perianal pruritus is most often reported; migration to the vagina may occur in females, p roducing local irritation. Attachment of adult worms to the intestinal wall ematodes Roundworm Strongyloides stercoralis Epidemiology This roundworm s geogr aphic distribution includes the tropics, subtropics, and the southern Unites Sta tes.

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Larvae penetrate the skin, causing a local skin reaction. After penetrating the skin, they migrate via lymphatics and venules to the alveo li, presenting 1 week later with respiratory symptoms.

The larvae continue trave enterobius vermicularis drug of choice through the respiratory tract until they are swallowed. Once in the small i ntestine, they mature to adults, and 2 weeks later diarrhea begins.

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The organism invades the small bowel mucosa, speci? Clinical Presentation Although often asymptomatic, healthy children may present with mild diarrhea and abdominal discomfort.

Immunosuppressed or malnourished pa tients may present with a more serious infection characterized by sepsis, shock, and pulmonary and neurologic disease, which may be fatal.

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Dissemination of the infection may occur in patients receiving steroids or immunosuppressant therapie s.