About 6 million pa- tients with cancer die every year worldwide. In recent years, the rate of cancer detection has raised up because of progression in diagnostic technologies 1.
Gynecological malignancy involving vaginal cancer is hpv cancer risk and the most victims are reported from developing countries 2. There are different risk factors including smoking, poor hygiene, hpv cancer risk parity, intimating with several sexual partners, in utero exposed diethylstilbestrol, immu- nodeficiency, genital warts and sexually transmitted Human Papilloma Virus HPV that predispose vaginal cancer.
The condom does not prevent the transmis- sion of HPVs; because the HPVs are able to transmit throughout genital skin to skin contact. The HPV not only in women but also in men may cause genital cancers.
Ginecologie minim-invaziva 1 Apply Ginecologie minim-invaziva filter HPV și cancerul de col uterin HPV - Human Papilloma Virus — este un virus comun care se transmite prin contact sexual vaginal, oral sau anal. Infecţia persistentă cu HPV reprezintă cauza principală hpv cancer risk cancerului de col uterin. Sunt descrise aproape 40 de genotipuri care pot fi localizate la nivelul organelor genitale atât la bărbat, cât şi la femeie, precum şi în faringe şi cavitatea bucală, determinând infecţii asimptomatice. Genotipurile diferă prin gradul de risc conferit post-infecţie pentru dezvoltarea cancerului: genotipuri de HPV cu grad ridicat de risc - hpv cancer risk risk - determină la femei modificări ale celulelor de la nivelul zonei cervico-vaginale şi pot duce la dezvoltarea cancerului de col uterin genotipuri de HPV cu grad scăzut de risc - low risk - pot duce la apariţia condiloamelor acuminate condilomatoza genitală De cele mai multe ori sistemul imun reuşeşte să elimine virusul în aproximativ 2 ani, înainte ca acesta să producă probleme de sănatate. Persistenţa infecţiei cu HPV pentru mai mulţi ani poate să duca la apriţia cancerul de col uterin.
The virus is ubiquitous and hpv cancer risk be isolated from different human races and animals 9. The earlier recognition of vaginal cancer was introduced in by Meigs and Graham.
Pentru majoritatea oamenilor, virusul papilomavirus uman HPV dispare de la sine, în mod spontan. Dar pentru alții care nu elimină virusul, anumite tipuri de HPV pot provoca cancere cervicale, vaginale și vulvare la femei și cancer anal la bărbați și femei.
However, the illustration of primary vaginal cancer was achieved by Cruveilhier in 19th century. This type of cancer is often known as the secondary gynecological disease which may occur hpv cancer risk the consequence of metastasis from cancerous anus, cervix, colon, endometrium, ovary, rectum and vulva in women.
Thus, the hpv cancer risk form of vaginal cancer is rare 6,10, There are different types of primary vaginal cancers Table 1 The previous reports show that squamous cell carci- noma ranks as the most prevalent vaginal cancer with the percentage of about The majority of squamous cell carcinoma is in association with HPV 6.
The average age of mortality for patients with vaginal cancer is recorded about 65 years old 6, There is a direct associa- tion between HPV and cervico-vaginal cancer. In utero contact diethylstilbestrol is the predominant hpv cancer risk of vaginal cancers of melanoma and adenocarcinoma 3,6, HPV family includes more than carcinogenic and non-carcinogenic types.
HPVs have positive tropism to human mucosal and moist membranes and skin. The low risk carcinogenic types of HPVs are important causative agent for viral warts such as genital warts Table 2 3,9, The aim of this article is to review the subtitle of vaginal cancer staging, epidemiology of HPV vaginal cancers, viral characteristics and pathogenesis of HPV vaginal cancers, clinical demonstrations of HPV vaginal cancers diagnosis, treatment and prevention.