Hpv virus in pap smear


hpv virus in pap smear

Material and methods: We have analyzed all cases with ACG who attended our colposcopy clinic between All cases were followed for a period of at least 36 months after the diagnosis of AGC on Pap smear.

Medical records were reviewed to determine the clinical data, colposcopy findings and histology results.

The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation.

Normal colposcopy, minor colposcopy changes, major colposcopy changes and suspicion of invasion were encountered in 44 cases The colposcopy hpv virus in pap smear not satisfactory transformation zone type III in 13 cases Conclusions: The ACG diagnosis needs new strategies in order to reduce the overtreatment but not to increase the false negative results.

Colposcopy is useful in cases with associated squamous cervical lesions, but new diagnostic tools are mandatory for a better hpv virus in pap smear.

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A possible one is represented by Human Papilloma Virus test, but the place of this test should be clarified by further studies. Author Biographies D.

Cervical cytology reported as negative and risk of adeno-carcinoma of the cervix: no strong evidence of benefit.

According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3]. Structura HPV women. Fig 1.

Br J Cancer ; Adenocarcinoma in situ of the cervix: management and outcome. Gynecol Oncol ; Cervical cancer in the Netherlands decrease of squamous cell carcinoma in older women, increase of adenocarcinoma in younger women.

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Int J Cancer ; Raab SS. Can glandular lesions be diagnosed in pap smear cytology?

Diagn Cytopathol ques oxiuros Kurman RJ, Solomon D eds.

New York: Springer, The Bethesda System: terminology for reporting results of cervical cytology. JAMA ; The role of cervical cytology and colposcopy in detecting cervical glandular neoplasia. Cytopathology ; Atypical glandular cells of undetermined significance: clinically significant lesions and means of patient follow-up.

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Cancer 25; Clinical significance of atypical glandular cells on cervical cytology. Obstet Gynecol ; European guidelines for quality assurance in cervical cancer screening: recommendations for clinical management of ab-normal cervical cytology, part 1.

Involvement of Human Papillomavirus genome in oncogenesis of cervical cancer

Cytopathology ; 1: Colposcopy of adenocarcinoma in situ and invasive adenocar-cinoma of the cervix. Obstet Gynecol Clin North Am ; BJOG ; Evaluation of atypical glandular cells of undetermined significance: is age important? Am J Obstet Gynecol ; Human papillomavirus DNA detection and histological findings in women referred for atypical glandular cells or adenocarcinoma in situ in their Pap smears.

Use of human papillomavirus testing in the management of atypical glandular cells. Hpv virus in pap smear Low Genit Tract Dis ; J Cancer Educ ; Atypical glandular cells of undeter-mined significance: a five-year retrospective histopathologic study.

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Preliminary results of the first cervical cancer screening programme in the North Eastern region of Romania. J Med Screen ; Perception and use of Pap smear screening among rural and urban women in Romania.

Prevenirea cancerului de col uterin HPV și cancerul de col uterin Cancerul de col uterin se dezvoltă atunci când celulele cervicale devin anormale, apoi se schimbă și devin canceroase.

Eur J Public Health ;