Unfortunately, it does not have specific signs and symptoms, being associated with an aggressive evolution and a poor prognosis if left untreated. Their results suggest that PD-1 and PD-L1 could be potential biomarkers for targeted treatment in some patients diagnosed with diffuse large B-cell lymphoma.
Malignant lymphomas of the head and neck may raise therapeutic difficulties. OIU, Vlad D. In the last five years from 1st of January to 31st of Decemberwe noticed 6 cases of rectal cancer, developed in patients who underwent stoma reversal more than two years before, for different pathologies.
The objective of the study. That was a starting point to analyze whether the restoration of a total digestive diversion, well known to improve life quality, also increases the risk of malignancy.
Thyroid disorders. Part III: neoplastic thyroid disease.
Material and methods. Our study showed that stoma reversal increase the risk of developing a rectal malignancy two years from restoration. We recommend annual control by recto-sigmoidoscopy both in patients with terminal permanent colostomy and papillary lesion of biopsy those with stoma reversal, in order to early discover a subsequent rectal cancer.
PD-L1 expression most often correlates with a poor prognosis and a PD-1 regulatory factor that mediates immunosuppression. The objective of this study was to describe the correlation between PD-1 and PDL-1 with survival in patients with the diagnosis of diffuse large B cell lymphoma.
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We found that there is a tendency of decreased survival and therapeutic response in DLBCL patients, with both an intense and weak PD-L1 positivity in tumor cells. PD-1 low positivity was associated in higher percentage with relapse and treatment unresponsiveness. Conclusions: Our data suggested that PD-L1 expression correlates with a poor clinical response although it is not an independent prognostic marker and PD-1 represents a favorable prediction factor for survival.
Drug therapy in papillary lesion of biopsy thyroiditis Author cancer parede abdominal Michael I. papillary lesion of biopsy
Romanian Journal of Internal Medicine
Autoimmune thyroiditis AIT is one of the unsolved problems of modern endocrinology, the etiology and pathogenesis being still insufficiently known. To study the effects of substitution, antioxidant and lymph-drainage therapy on the structure and function of the thyroid gland in patients with AIT and hypothyroidism. We have identified 2 groups of patients with AIT and subclinical hypothyroidism. The first group papillary lesion of biopsy control group — included 20 patients who received substitution therapy with thyroxine.
The second group included 33 patients who received a comprehensive treatment with thyroxine, alpha lipoic acid and Lymphomyosot. The use of substitution therapy with thyroxine and the proposed antioxidant and lymph drainage therapy in patients with AIT led to the improvement of the structure of the gland, reduced the activity of peroxide oxidation processes and the activity of pro-inflammatory cytokines, increased the level of antioxidant defense enzymes, normalized the number of aniline-positive lymphocytes, improved the lymphatic drainage function of the gland.
Our results sustain the effectiveness of the proposed method of complex treatment in patients with autoimmune thyroiditis. Ghrelin level and types of eating behavior when combined papillary lesion of biopsy irritable bowel syndrome, arterial hypertension and obesity Author : Vasyl G.
However, its cardioprotective effect, as well as vasodilatory action and participation in arterial pressure regulation, are not sufficiently studied. To study fasting and postprandial ghrelin levels and eating behavior in patients with comorbidities such as irritable bowel syndrome, arterial hypertension, and obesity.
Materials and methods. The study included 24 patients with irritable bowel syndrome, constipation and normal body mass index, 18 patients with arterial hypertension and obesity, and 54 patients with irritable bowel syndrome, constipation, arterial hypertension, and obesity.
Papillary lesion of biopsy pressure monitoring was performed in all patients and fasting and postprandial ghrelin levels in blood serum were measured, as well as eating behavior type, using the Dutch Eating Behavior Questionnaire.
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Results of hour blood pressure monitoring showed a more significant rise in blood pressure, as well as a predominance of the non-dipper profile, encountered in The increased level of postprandial serum ghrelin in patients with this comorbid pathology contributes to the predominance ofexternal and emotional types of eating behavior, which were found in papillary lesion of biopsy The studied combined pathology irritable papillary lesion of biopsy syndrome with constipation, arterial hypertension, and obesity is accompanied by higher blood pressure, non-dipper blood pressure profile predominance, increased postprandial ghrelin level and eating disorders.
High-grade serous carcinoma of the ovary is an aggressive form of cancer, with unknown precursor lesions and often delayed diagnosis because of non-specific, mild symptoms.
Atypical ultrasound appearance of benign breast nodules
We performed a clinical-pathological study of ovarian high-grade serous carcinomas, in order to evaluate morphological and new immunohistochemistry characteristics of this malignancy. This is a retrospective study of 10 cases of ovarian high-grade serous carcinoma.
Mean age was Maximum tumor diameter was 16 cm. We noticed one case with pleural metastasis M1.
The majority of patients papillary lesion of biopsy ovarian high-grade serous carcinomas presented with extraovarian extension and were characterized by high mitotic index, rare presence of psammoma bodies, AR expression Bilateral breast carcinoma — a study of patients admitted in a papillary lesion of biopsy emergency hospital Author : Oana C. Breast carcinoma represents the leading cause of oncologic dysbiosis crohns disease among women worldwide.
Bilateral breast carcinoma is a distinct pathologic entity, with particular prognostic and therapeutic implications.
The objective of the study was to determine the histologic and immunohistochemical characteristics of patients with bilateral breast carcinoma admitted in a university emergency hospital from Bucharest, Romania. We analyzed breast carcinoma specimens registered as bilateral in the Department of Pathology of the University Emergency Hospital, Bucharest, Romania, betweenand studied their histologic and molecular features in the clinical context obtained from our hospital database.
The term of verrucous pigmented lesions includes a series of non-melanocytic and melanocytic, benign and malignant lesions. Among these, the most frequent is the seborrheic keratosis, a common epidermal tumor, affecting the sun exposed areas of adult. In this work we present the clinical and dermoscopical aspects of three cases of verrucous pigmented lesions two seborrheic keratoses and one seborrheic keratosis-like melanoma that determined the diagnostic algorithm as well as the therapeutic approach.
All the analyzed patients were postmenopausal women. The extent of time between the diagnosis of the first and second tumor varied in metachronous cases from 8 months to 7 years. In the majority of cases, the bilateral breast lesions shared histologic, grading and hormone expression similarities. Bilateral breast carcinoma is a rare entity that needs more histologic parameters to be defined as primary or metastatic.
Atlas of Breast Pathology
The purpose of the study was to determine whether the following 4 factors: age, sex, type of intervention and type of dialysis acute or chronichave an influence on the number of dialysis sessions associated with urological interventions.
The study included almost patients undergoing dialysis, during a 3 year period, in 3 university hospitals in Bucharest, Romania. In the end, after applying the inclusion and exclusion criteria, the study group consisted of 89 patients. The time frame in which the number of dialysis sessions was evaluated started from the moment the patients entered urological surveillance for undergoing a urological intervention until the patients where discharged.
Out of the 4 factors, the following statistically significant differences were encountered: the mean number of dialysis sessions was lower in papillary lesion of biopsy under 50 years than in those older than 69 years p InterleukinA and Papillary lesion of biopsy level in the blood serum papilomatosis de piel patients with different clinical course of Rosacea Author : Maryna V.
Rosacea is a common chronic dermatosis characterized by papillary lesion of biopsy of open areas of the skin face and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines — interleukinA ILA and interleukin IL in the serum of patients with rosacea, depending on the nature of the clinical course of dermatosis.
The study involved 36 patients with rosacea, 17 of them diagnosed with erythema-telangiectatic form and 19 with papulo-pustular form of rosacea. In 18 patients, the dermatosis lasted for up to 6 months, in the papillary lesion of biopsy 18 patients for more than 6 months.