Papillary thyroid carcinoma usg, Characterization of thyroid nodules in acromegalic patients


Background: Thyroid nodules were reported with high prevalence in acromegalic patients.

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Patients and methods: 63 acromegalic patients 16 males and 47 femalesaged at diagnosis Median duration of acromegaly was 8 years. Thyroid ultrasound was performed.

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In suspected nodules, pathological examination either fine needle aspiration with cytology exam or pathology exam papillary thyroid carcinoma usg thyroidectomy was performed.

Results: Median thyroid volume was Thyroid nodules were present in 52 patients Multiple thyroid nodules were found in 45 out of 52 cases Toxic multinodular goiter was prezent in 5 patients 7. Average maximum diameter of dominant nodule was 1.

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Thyroid differentiated cancer was diagnosed in 6 patients 9. Histological type was papillary carcinoma: 3 macrocarcinomas and 3 microcarcinomas follicular variant of papillary carcinomas ; two microcarcinomas were multifocal.

Five patients with thyroid carcinomas underwent thyroidectomy; 4 patients two macrocarcinomas and two multifocal microcarcinomas also received radioiodine treatment.

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Thyroid surgery is pending in one patient. Autoimmune thyroiditis was present in 4 patients 6. Conclusion: Multinodular nontoxic thyroid disease was very frequent in our series of acromegalic patients.

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We also found an increased prevalence of differentiated thyroid carcinoma. Careful clinical thyroid examination, thyroid ultrasound and cytological exam were recommended in acromegalic patients. This Volume.

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