Department of Ophthalmology, Grigore T. E-mail: moc.
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We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.
The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence.
Cancerul este o maladie care, descoperita timpuriu, ofera un procent semnificativ de vindecari. Rata de mortalitate datorata cancerului de col uterin a scazut in ultimii papilloma vs neoplasm in tarile dezvoltate, ca rezultat al depistarii precoce si a modernizarii mijloacelor de tratament. In tara noastra acest neoplasm are o incidenta scazuta, dar in multe cazuri este descoperit in faze avansate. In Romania acest cancer ocupa locul al doilea in randul neoplaziilor sexului feminin, dupa cancerul mamar. Infectia cu Human Papilloma Virus HPV este unul dintre factorii de risc implicati in aparitia cancerului de col uterin.
Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little explored territory.
Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells. Case Report We present a unique case of squamous cell carcinoma papilloma vs neoplasm the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
Dacă se suspectează cancerul cervical sunt necesare efectuarea mai multor investigații pentru a confirma papilloma vs neoplasm diagnostic: colposcopia și biopsia cervicală — identifică și determina localizarea exacta a celulelor maligne de la suprafața cervixului; Biopsia endocervicală — determină prezența celulelor maligne și la nivelul canalului cervical porțiunea care leagă cervixul de corpul uterin. Aceste investigații pot fi realizate și în cazul femeilor însărcinate suspecte de cancer cervical. Stadiile cancerului cervical După depistarea cancerului se efectuează diverse investigații pentru a afla gradul de răspândire în cervix sau în alte părți ale corpului, iar metoda prin care se studiază se papilloma vs neoplasm stadializare. Informațiile culese din procesul de stadializare hotărăsc stadiul bolii și sunt importante pentru planificarea tratamentului.
He has been treated for the last 2 months with dexamethasone eye papilloma vs neoplasm for scleritis by another ophthalmologist. The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses.
All other ophthalmological findings were normal. Conjunctival culture was performed before surgery, and no bacterial infection papilloma vs neoplasm found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.
The limbic lesion was removed surgically papilloma vs neoplasm 2 mm margin of normal tissue and diathermy of the adjacent sclera was done.
At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate differentiated papilloma vs neoplasm squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.