Recurrent respiratory papillomatosis vocal folds


Diagnostic si simptome

Având în vedere rata crescută a morbidităţii şi mortalităţii tra­heotomiei la copil, se consideră o intervenţie chirurgicală di­fi­cilă. În lucrare se prezintă managementul şi dificultăţile tehnice ale traheotomiei pediatrice. Material şi metodă. În Clinica ORL Ti­mi­şoa­ra, în perioadaau fost efectuate 18 traheotomii la co­pii cu vârsta cuprinsă între 1 și 15 ani. Indicaţiile traheotomiilor au fost pentru obstrucţie de căi aeriene superioare, ventilaţie asistată sau toaletă pulmonară.

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Au fost utilizate diferite tipuri de canule tra­he­ale. Alegerea canulelor trebuie să ţină cont de indicaţia tra­heo­to­miei. Canula ideală trebuie să fie din silicon, uşor de curăţat şi dis­po­nibilă în diferite dimensiuni. Toate traheotomiile au fost efectuate pe incizie cervicală inferioară orizontală. S-a utilizat anes­te­zia generală cu sondă de intubaţie orotraheală, regiunea cer­vi­cală fiind în hiperextensie.

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Complicaţiile intraoperatorii au fost minime: uşoa­re hemoragii şi probleme recurrent respiratory papillomatosis vocal folds canulele traheale. Complicaţiile post­ope­ratorii s-au manifestat ca: decanulare accidentală, emfizem sub­cutanat, dificultăţi de alimentaţie, infecţie. Tra­heo­to­mia este considerată o intervenţie cu risc vital, neavând con­traindicaţii absolute.

Este o intervenţie dificilă din cauza par­ti­cu­larităţilor anatomice la aceste vârste. Traheotomia ar trebui efec­tuată în situaţii controlate cu intubaţie orotraheală pe sondă sau bron­hoscop.

Cuvinte-cheie: traheotomie, copil, canulă, complicaţii Eustachian tube causes Adriana Neagoş MD, PhD, University of Medicine and Pharmacy Târgu-Mureş, Otorhinolringology Department, Târgu-Mureş, Romania Eustachian tube is an important source of middle ear pathogenesis and has been linked to causing middle ear and mastoid aeration pathology.

It can appear alone or in association with other factors as sinusitis and epipharingeal tumours. Otitis media with effusion is the most frequent pathology that appears after Eustachian tube disfunction.

Bors Factorii

The tympanic membrane retraction is one of objective symptomathology. Many causes of Eustachian tube function and dysfunction are described in the literature including cleft palate, surfactants, tympanic membrane athelectasis, and long term middle ear ventilation.

The epidemiological studies illustrated that poor Eustachian tube function plays a major role in the pathogenesis of otits media, so it is very important to have a good function of the tube before and after a surgical procedures.

  • Papilomatoza laringian se prezint sub forma unor multiple formaiuni tumorale papilare la nivelul corzilor vocale, de unde se pot extinde spre benzile ventriculare, epiglot.
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Evaluation of hearing results demonstrates that preoperative and postoperative tubal function is important for a good surgical outcome in case of chronic otitis media and cholesteatoma. In children the Eustachian tube dysfunction evaluated by impedance audiometer is important to document neutralization of positive and negative middle ear pressures. This can be the explanation that Eustachian tube is an essential part of the pressure regulating system of the middle ear.

Papilom de coardă vocală

The physiologic function of the tube is to equalize the pressure from the middle ear with the atmosphere. The Eustachian tube closing failure and recurrent respiratory papillomatosis vocal folds induction of negative middle ear pressure are important factors in the development of chronic ear disease. Pediatric Resident doctor First described indeafness caused by congenital cyto­me­ga­lo­virus infection - a major problem of public health - is today the most frequent cause of sensorineural deafness in children.

The pre­valence of congenital cytomegalovirus infection is between 0.

Much more than documents.

Diagnosis of congenital cytomegalovirus in­fection is possible if the virus is isolated during the first 3 weeks of life or if the serum IgM antibodies are found at birth or shortly af­ter birth.

Deafness caused by cy­to­megalovirus infection can be progressive or with late onset at pre­schoolers or in the first years of schoolrequiring more frequent audio­logy monitoring at birth, at 3, 6, 9, 12, 18, 24, 30, and 36 months and annually until school age in order to detect and to treat deaf­ness.

Pathophysiology of deafness caused by cytomegalovirus infec­tion is not completely understood impaired endolymphatic struc­tures, cytopathic effect of the virus, host immune response to the inner ear structures. Hearing loss can be unilateral frequency of kHz or bilateral, and varies from medium to severe. Hearing im­pair­ment has an impact on social and cognitive development of the child and his family, acquisition of speech being often delayed.

The risk of permanent sequelae in case of symptomatic infection is higher in children from mothers suffering of primary infection, but disabilities were observed also in children from mothers with non-primary infections.

In children with asymptomatic congenital cy­to­megalovirus infection, increased virulence in the first month of life is associated with sensorineural deafness.

Robert Hillman to develop a portable voice monitoring system for assessing voice disorders. The system uses a small non-invasive sensor placed on the neck that plugs into a smartphone. We are recruiting patients with muscle tension dysphonia no lesions or vocal fold nodules must be bilateral lesions to participate in this study.

Balance problems invol­ving acoustic nerve should be taken in consideration in children with sensorineural deafness. The relation between high viral charge in infants and deafness probability recurrent respiratory papillomatosis vocal folds the role of antiviral the­rapy in decreasing the incidence and the severity of deafness caused by cytomegalovirus.

Oral Valganciclovir represents today an al­ter­native to Ganciclovir, cancer care ingrasa used intravenous. Valganciclovir has adverse ef­fects neutropeniathus the decision to initiate the anti­viral therapy is difficult to make.

recurrent respiratory papillomatosis vocal folds

Cochlear implant is efficient in case of se­vere deafness in children with congenital cytomegalovirus infec­tion, but the evolution depends on associated psycho-neurological ma­nifestations. Keywords: infection, cytomegalovirus, deafness, child Difficulties in the diagnosis of hearing loss in children Raluca Enache ENT Sarafoleanu Medical Clinic, Bucharest, Romania Hearing represents an important bacterii wc and cognitive function, the hear­ing loss being an important health problem worldwide.

Hy­po­a­cusis is a common pathology found in both adults and children. Given these implications, the diagnosis papiloma humano como empieza hearing loss in children must be done correctly and ra­pidly.

The assessment of the auditory function is indicated in patients with subjective complaints and in those recurrent respiratory papillomatosis vocal folds belong to groups supposed to be at risk for a hearing loss.

Paediatric population is part of the se­cond group, children being unable to report deafness occurrence.

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Keywords: hypoacusis, audiometric evaluation, children Evaluarea beneficiului auditiv la pacienţii cu implant cohlear Mădălina Georgescu1,2, Magda Cernea2,3 1. Surditatea bilaterală in­sta­lată în primii doi ani de viață determină instalarea unui al doilea han­dicap senzorial - mutitatea, asociere care impietează grav asupra dez­voltării ulterioare a copilului pe multiple planuri: educațional, social și economic.

Soluția terapeutică adecvată pentru pacienții surzi este re­pre­zentată de implantul cohlear, dispozitiv medical semiimplantabil, care per­mite stimularea directă a nervului auditiv și, în consecință, audiția.

Eva­luarea beneficiului auditiv al implantului cohlear nu trebuie să se li­mi­teze la evaluarea pacienților implantați prin audiogramă tonală, ci, obli­gatoriu, prin audiogramă vocală, singura în măsură să redea nivelul abilitării auditive în toată complexitatea sa.

Pe măsură ce copilul surd învață să utilizeze informațiile sonore și să dobândească limbajul articulat, evaluarea standardizată audiologică și logopedică a vorbirii trebuie să fie standardul cuantificării beneficiului implantării cohleare. Prezentăm în lucrare rezultatele obținute în I. Sunt prezentate elemente de tehnică chirurgicală apli­cate în cazul diferitelor entități patologice, pornind de la vegetațiile ade­noide și recurrent respiratory papillomatosis vocal folds la patologia bazei craniului.

Recurrent respiratory papillomatosis vocal folds insistă pe pre­zen­tarea modalităților de tratament, pregătire preoperatorie și îngrijiri post­operatorii în cazul patologiei tumorale, cu accent pe prezentarea par­ti­cularităților fibroamelor nazofaringiene.

recurrent respiratory papillomatosis vocal folds picture of papilloma on eyelid

Se­ve­ral substances also can be analysed in saliva and this technique offers some ad­vantages. Saliva sampling can be done anytime, anywhere and multiple collection and assessment of samples during the day could offer a better understanding of daily production of the biomarkers of the endocrine and autonomic nervous systems. Salivary biomarker measures represent a reliable method of investigating hypothalamo-pituitary-adrenal axis and autonomic nervous system activities, avoiding the stressful event of venipuncture and offering the possibility of self-collection by subjects.

The aim of this presentation is to encourage the use of salivary biomarkers assays in clinical practice and research and also to provide background information on some methodological factors that influence and add variance to bio­marker outcome measurements.

In fact, numerous methodological factors could influence human neuro-endocrine measurements and, consequently, can dramatically compromise the accuracy and validity of research. These factors can be categorized into those that are biologic and recurrent respiratory papillomatosis vocal folds that are procedural-analytic in nature.

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For example, traces of blood might interfere with the results of saliva testing. One major problem, the lack of compliance sometimes seen in outpatient saliva donors, requires strict standardization of recurrent respiratory papillomatosis vocal folds collection and analysis methods to achieve better comparability and assessment of published salivary hormone data. Such effort includes the development of specific and standardized analytical tools, the es­ta­blish­ment of defined reference intervals, and implementation of round-robin trials.

Keywords: salivary biomarkers, hypothalamo-pituitary-adrenal axis, au­to­no­mic nervous system, saliva testing Sleep pathology in children - practical elements Adriana Neagoş MD, PhD, University of Medicne and Pharmacy Târgu-Mureş, Otorhinolaringology Department, Târgu-Mureş, Romania Sleep is important to children, contributing to their physical and men­­tal growth.

There are many possible causes for the development of obstructive sleep apnea in children. Obstructive sleep apnea syn­drome OSAS in children has different effects, including deficits in cog­­nition and neuropsychological functions, learning problems, hyperactivity, and nocturnal enuresis. Obstructive sleep apnea in children cha­rac­te­rized by a combination of partial and intermittent obstruction of the upper airway can disturb sleep and normal ventilation.

recurrent respiratory papillomatosis vocal folds internare dezintoxicare

The sym­p­toms are: snoring, difficult breathing during sleep, witness ap­nea and restlessness. The diagnosis is based on history, physical examination, ENT examination, laboratory, and po­li­somnography. Recurrent respiratory papillomatosis vocal folds clinical and paraclinical investigations must to be correlated, before establishing the diagnosis, and to evaluate the degree of upper airways obstruction.

Hypertrophy of the adenoids and tonsils is a major cause of OSAS in children. These include hyper­trophy of the tonsils and syndromes such as Down syndrome, Pickwickian syndrome, Prader-Willi syndrome or Marfan syndrome. However, OSAS can also be the result of obesity, midfacial dysplasia, retro- or micrognathia, allergic rhinitis or muscular dystrophy.

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Snoring and obstructive sleep apnea are frequent problems not only in adults, but also in children and adolescents, as can be seen from current epidemiological data. Corrective surgery is possible for rare mal­for­ma­tion syndromes.

Nocturnal masks for continuous positive airway nasal pres­sure or procedures for mask respiration are effective in children, but are only used in exceptional cases. Dysregulations of the physiological rhythms are thought to play a role in the initiation or progression of some diseases, therefore, we wished to explore HPA axis function in children recurrent respiratory papillomatosis vocal folds obstructive sleep apnea OSA.

The results showed that the salivary cortisol con­cen­tration measured in the control group reflected a typical course of the salivary cortisol diurnal trajectory, with the evening va­lue being significantly lower than the value in the morning. The mild and moderate OSA groups showed a comparable trend with a sig­ni­fi­cant diurnal decrease in salivary cortisol concentration du­ring the day. Moreover, we report here that the salivary cortisol con­cen­tra­tion measured in the morning, in both the moderate and mild OSA groups, was significantly higher than that in the control group.

In con­clusion, we showed overall significant and severity-dependent in­creases in salivary cortisol production.

The Larynx, Volume I

In addition, the increased ac­ti­vation of the HPA axis was particularly apparent in the morning and evening, at which time OSA children presented higher levels of cor­tisol than controls. Keywords: hypothalamus-pituitary-adrenal axis, salivary cortisol, obstructive sleep apnea, children Preclinical indicators of autonomic nervous system activity in pediatric osa Lucia Corina Dima-Cozma1, Sebastian Cozma2, Cătălina Elena Lupușoru3, Francesca Romana Patacchioli4, Cristina Mihaela Ghiciuc3 1.

The aim of the present study was to explore the interdependencies of the recurrent respiratory papillomatosis vocal folds axes and the reliability of salivary alpha-amylase as a noninvasive marker of autonomic nervous sys­tem activation.