The incidence of GEP-NENs has increased worldwide over the past decades, with gastric cancer kinds small intestine, rectum, and pancreas as the most common tumor locations.
Archive of Clinical Cases
The epidemiological characteristics, pathogenesis and treatment have raised many questions, and some of them are still being debated.
Here, we report a case of gastric collision tumor with large-cell neuroendocrine carcinoma and adenocarcinoma. A year-old male patient with a history of gastric resection performed 30 years ago, with no medical records revealing the type of resection or the reconstructive way, presented with epigastric pain.
The endoscopy revealed a solid, ulcerated mass at the gastrojejunal anastomosis site from which a tissue biopsy was taken, which was reported as adenocarcinoma. For staging, the patient underwent an abdominal CT scan, which showed the thickening of the gastric wall adjacent to anastomosis and perilesional adenopathy.
The patient underwent a subtotal gastrectomy and regional lymphadenectomy.
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A diagnosis of large-cell neuroendocrine carcinoma developed on the gastric stump associated with isolated foci of moderately differentiated tubular adenocarcinoma pT3N1G3 was made. Immunohistochemical analysis is essential for the diagnosis and classification of the lesion. To confirm the diagnosis, Chromogranin A and Synaptophysin are needed, and for prognostic evaluation the identification of Ki and mitotic figure count are required. Controversies in the treatment of digestive neuroendocrine tumors.
Gastric cancer kinds Cancer Metasta Treat ; Neuroendocrine neoplasms of the gastrointestinal tract. Dtsch Arztebl Int ; 18 TNM staging of foregut neuro endocrine tumors: a consensus proposal including a grading system.
Virchows Arch ; 4 WHO classification of tumours of the digestive system, 4th Edition.
Lyon: IARC, Does the WHO classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas? J Gastroenterol ; 50 5 A case of gastric cancer with neuroendocrine carcinoma, signet ring cell carcinoma components, and intramural metastases.
Informatii generale si recomndari gastric cancer kinds efectuarea testului genetic Cancerul gastric este al patrulea cancer ca frecventa si reprezinta a doua cauza de mortalitate prin cancer la nivel mondial, cu aproximativ decese anual. Tumorile gastrice sporadice se dezvolta printr-un proces ce implica mai multe etape, in care gastrita cronica conduce la atrofie, apoi la metaplazie intestinala si in cele din urma la displazie; tumorile sunt de obicei exofitice, adesea ulcerante si localizate in portiunea distala a stomacului.
Am J Case Rep ; Mixed adeno-neuroendocrine carcinoma; case series of verrues plantaires et papillomavirus patients with review of the literature. Balkan Med J ; 35 3 Gastoroenterostoma after Billroth anterectomy as a premalignant condition. World J Gastroenterol ; 18 25 — Neuroendocrine carcinoma of the stomach morphologic and immunohistochemical characteristics and prognosis. Am J Surg Pathol ; 37 7 Gastric mixed gastric cancer kinds carcinoma with a good prognosis.
Inter med ; Gastric neuroendocrine tumor: review and update. Arq Bras Cir Dig ; 30 2 Surgical treatment and prognosis of gastric neuroendocrine neoplasms: a single-center experience. BMC Gastroenterol ;
In this study, our propose was to evaluate the histopatological changes corellated with immunohistochemical results demonstrating the types of cellular infiltration and proliferative activity of gastric mucosa infected with H. Material and method: Gastric endoscopic examinations was performed in patients with anti-H. Snippets harvested endobiopsic stomach were fixed in formalin and processed by paraffine inclusion.