Unfortunately, it does not have specific signs and symptoms, being associated with an aggressive evolution and a poor prognosis if left untreated. Their results suggest that PD-1 and PD-L1 could be potential biomarkers for targeted treatment in some patients diagnosed with diffuse large B-cell lymphoma.
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Malignant lymphomas of the head and neck may raise therapeutic difficulties. OIU, Vlad D.
In the last five years from 1st of January to 31st of Decemberwe noticed 6 cases of rectal cancer, developed in patients who underwent stoma reversal hpv 16 virus loswerden than two years before, for different pathologies.
The objective of the study. That was a starting point to analyze whether the restoration of a total digestive diversion, well known to improve life quality, also increases the risk of malignancy. Material and methods.
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Peritoneal cancer of gynecological origin study showed that stoma reversal increase the risk of developing a rectal malignancy two years from restoration. We recommend annual control by recto-sigmoidoscopy both in patients with terminal permanent colostomy and in those with stoma reversal, in order to early discover a subsequent rectal cancer.
PD-L1 expression most often correlates with a poor prognosis and a PD-1 regulatory factor that mediates immunosuppression. The objective of this study was to describe the correlation between PD-1 and PDL-1 with survival in patients with the diagnosis of diffuse large B cell lymphoma.
The purpose of this paper is to quantify the incidence of different histological types of ovarian tumors and to demonstrate the clinical importance of an effective screening program, considering the paucisymptomatic nature of this pathology. The incidence of ovarian epithelial tumors varied across age groups, our study group including women aged between 34 and 64 years old. Knowing the age distribution plays an important role in the implementation of screening programs.
We found that there is a tendency of decreased survival and therapeutic response in DLBCL patients, with peritoneal cancer of gynecological origin an intense and weak PD-L1 positivity in tumor cells.
PD-1 peritoneal cancer of gynecological origin positivity was associated in higher percentage with relapse and treatment unresponsiveness.
Conclusions: Our data suggested that PD-L1 expression correlates peritoneal cancer of gynecological origin a poor clinical response although it is not an independent prognostic marker and PD-1 represents a favorable prediction factor for survival.
Drug therapy in autoimmune thyroiditis Author : Michael I.
A clinical-pathological study of ovarian tumors - one-year center experience
Autoimmune thyroiditis AIT is one of the unsolved problems of modern endocrinology, the etiology and pathogenesis being still insufficiently known. To study the effects of substitution, antioxidant and lymph-drainage therapy on the structure and function of the thyroid gland in patients with AIT and hypothyroidism.
The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital. Materials and peritoneal cancer of gynecological origin. We analyzed 58 cases registered in the Pathology Department as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types. Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases of malignant tumors 39 cases of primary and 7 cases of secondary tumors. The most frequent histologic type was represented by high-grade serous carcinoma
We have identified 2 groups of patients with AIT and subclinical hypothyroidism. The first group — control peritoneal cancer of gynecological origin — included 20 patients who received substitution therapy with thyroxine. The second group included 33 patients who received a comprehensive treatment with thyroxine, alpha lipoic acid and Lymphomyosot.
The use of substitution therapy with thyroxine and the proposed antioxidant and lymph drainage therapy in patients with AIT led to the improvement of the structure of the gland, reduced the activity of peroxide oxidation processes and the activity of pro-inflammatory cytokines, increased the level of antioxidant defense enzymes, normalized the number of aniline-positive lymphocytes, improved the lymphatic drainage function of the gland.
Our results sustain the effectiveness of the proposed method of complex treatment in patients with autoimmune thyroiditis.
Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian
Ghrelin level and types of eating behavior when combined with irritable bowel syndrome, arterial hypertension and obesity Author : Vasyl G. However, its cardioprotective effect, as well as vasodilatory action and participation in arterial pressure regulation, are not sufficiently studied.
- Anatomy and Embryology Department University of Medicine and Pharmacy Iuliu Haåieganu, Clinicilor street Cluj Napoca, Romania Received: Accepted: Rezumat Introducere: Carcinomatoza peritoneală reprezintă un stadiu avansat al cancerelor abdominale în general şi a cancerului colorectal în particular.
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Она, разумеется, знала, что были и другие программы, над которыми он работал так долго, программы, создать которые было куда легче, чем нераскрываемый алгоритм.
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To study fasting and postprandial ghrelin levels and eating behavior in patients with comorbidities such as irritable bowel syndrome, arterial hypertension, and obesity.
Materials and methods.
The study included 24 patients with irritable bowel syndrome, constipation and normal body mass index, 18 patients with arterial hypertension and obesity, and 54 patients with irritable bowel syndrome, constipation, arterial hypertension, and obesity.
Blood pressure monitoring was performed in all patients and fasting and postprandial ghrelin levels in blood serum were measured, as well as eating behavior type, using the Dutch Eating Behavior Questionnaire.
Results of hour blood pressure monitoring showed a more significant rise in blood pressure, as well as a predominance of the non-dipper profile, encountered in The increased level of postprandial serum ghrelin in patients with this comorbid pathology contributes to the predominance ofexternal and emotional types of eating behavior, which were found in The studied combined pathology irritable bowel syndrome with constipation, arterial hypertension, and obesity is accompanied by higher blood pressure, non-dipper blood pressure profile predominance, increased postprandial ghrelin level and eating disorders.
High-grade serous carcinoma of the ovary is an aggressive form of cancer, with unknown precursor lesions peritoneal cancer of gynecological origin often delayed diagnosis because of non-specific, mild symptoms. We performed a clinical-pathological study of ovarian high-grade serous carcinomas, in order to evaluate morphological and new immunohistochemistry characteristics of this malignancy.
This papillomavirus femme definition a retrospective study of 10 cases of ovarian high-grade serous carcinoma. Mean age was Maximum tumor diameter was 16 cm.